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(Z)-5-((1-(4-Chloro-2-(trifluoromethyl)benzyl)-1H-indazol-5-yl)methylene)-3-(...
Janssen Pharmaceutica Nv innovator for the treatment of hyperglycemia in patients with type 2 diabetes mellitus. 2,4-Thiazolidinedione,...
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Whey beneficially affects diabetes and cardiovascular disease risk factors in...
Originally posted on lyranara.me: Whey protein has been demonstrated to improve fasting lipid and insulin response in overweight and obese individuals. To establish new hypotheses for this effect and...
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Lilly’s diabetes drug peglispro outshines world’s most popular insulin
insulin peglispro SYNONYMS macrogol 20000 pegylated insulin lispro: [28B-(6-N-{[ω-methoxypoly(oxyethylene)]carbonyl}-L-lysine), 29B-L-proline]human insulin CAS 1200440-65-8 antidiabetic; Lilly’s...
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How leptin, the ‘satiety hormone,’ reverses diabetes
Originally posted on lyranara.me: Treatment with leptin, the hormone associated with fullness or satiety, reverses hyperglycemia in animals models of poorly controlled type 1 (T1D) and type 2 (T2D)...
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Discovery of Imigliptin, a Novel Selective DPP-4 Inhibitor for the Treatment...
compd 27 (AS ABOVE) IN http://pubs.acs.org/doi/abs/10.1021/ml5001905 Imigliptin CAS OF FREE BASE 1314944-07-4 C21 H24 N6 O Benzonitrile,...
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A New Way to Treat Diabetes?
Type-2 diabetes is a severe metabolic disease caused by the loss of the cells producing the hormone insulin. Since this molecule controls the up-take of glucose from the circulation, diabetic patients...
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TA 1887 a highly potent and selective hSGLT2 inhibitor
6a-4 is TA 1887 TA 1887 CAS 1003005-29-5 Deleted CAS Registry Numbers: 1274890-87-7 C24 H26 F N O5 1H-Indole, 3-[(4-cyclopropylphenyl)methyl]-4-fluoro-1-β-D-glucopyranosyl-...
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Luseogliflozin, TS 071…………. strongly inhibited SGLT2 activity,
LUSEOGLIFLOZIN, CAS 898537-18-3 An antidiabetic agent that inhibits sodium-dependent glucose cotransporter 2 (SGLT2)....
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Lupin launches insulin glargine in India
Lupin launches insulin glargine in India: Indian pharma company, Lupin Limited announced a strategic distribution agreement with LG Life Sciences of South Korea to launch Insulin Glargine, a novel...
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FDA ALLOWS MARKETING OF FIRST ZNT8AB AUTOANTIBODY TEST TO HELP DIAGNOSE TYPE...
FDA allows marketing of first ZnT8Ab autoantibody test to help diagnose type 1 diabetes Today, August 20, 2014, the U.S. Food and Drug Administration allowed marketing of the first zinc...
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CARMEGLIPTIN………….a DPP-4 inhibitor
(2S,3S,11βS)-1-(2-Amino-9,10-dimethoxy-1,3,4,6,7,11β-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-(4S)-fluoromethyl-pyrrolidin-2-one Dihydrochloride...
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澳格列汀, SP2086, Retagliptin
澳格列汀, SP2086, Retagliptin 1174122-54-3(Retagliptin), 1174038-86-8 (Retagliptin Hydrochloride), 1256756-88-3（Retagliptin Phosphate)...
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DUTOGLIPTIN
Dutogliptin tartrate Syn name: 1-[N-[3(R)-Pyrrolidinyl]glycyl]pyrrolidin-2(R)-ylboronic acid L-tartrate Cas number: 890402-81-0 Molecular Formula: C14H26BN3O9 Molecular Weight: 391.18 DUTOGLIPTIN...
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DENAGLIPTIN
DENAGLIPTIN (2S,4S)-1-[(2S)-2- amino-3,3-bis(4-fluorophenyl)propionyl]-4-fluoropyrrolidine-2-carbonitrile, (2S,4S)-4-fluoro-1-[4-fluoro-beta-(4-fluorophenyl)-L-phenylalanyl]-2-pyrrolidinecarbonitrile...
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NAVEGLITAZAR (LY519818)
NAVEGLITAZAR 2(S)-Methoxy-3-[4-[3-(4-phenoxyphenoxy)propoxy]phenyl]propionic acid 476436-68-7 C25 H26 O6, 422.4703 CCRIS 9448 LY 519818 LY 9818 LY519818 LY9818 Naveglitazar UNII-Y995M7GM0G...
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GOSOGLIPTIN
GOSOGLIPTIN CAS 869490-23-3 FREE BASE DIHYDROCHLORIDE..869490-47-1 GOSOGLIPTIN; UNII-GI718UO477; PF-00734200; PF-734200;...
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EVOGLIPTIN
EVOGLIPTIN CAS: 1222102-29-5 FREE HCL……1246960-27-9 tartare.. 1222102 -51-3 Dong-A Pharmaceutical. Co., Ltd, 동아제약 주식회사 2-Piperazinone,...
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GEMIGLIPTIN
GEMIGLIPTIN 1-[2(S)-Amino-4-[2,4-bis(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one PHASE 3, DPP-IV inhibitor, Lg Life Sciences Ltd. CAS...
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ALOGLIPTIN
ALOGLIPTIN Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin (trade name Nesina in the US[1]...
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What is SBM-TFC-039 an SGLT Inhibitor from Sirona Biochem !!
A new “flozin” seems to me appearing on the horizon in form of SBM-TFC-039 an SGLT Inhibitor from Sirona Biochem, picked up a list from WO 2012160218, from TFChem…….see link , Sirona Biochem Announces...
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